Qabiilku wuxuu ka kooban yahay fitamiin B1 (thiamine hydrochloride) , fitamiin B12 (hydroxocobalamin) , fitamiin B6 (pyridoxine hydrochloride) . Waxay leedahay saameyn faa'iido leh oo ku saabsan shaqada beerka iyo habdhiska dareenka. Waxay kicisaa xinjirowga dhiigga ee qaadasho sare waxay sababtaa kororka thromboplastin iyo waxqabadka prothrombin.
Ficilka dawooyinka
Tribedoce) waxaa loola jeedaa koox fiitamiinno biyo-milmi kara. Waxay leedahay hawl bayooloji sare leh. Tribedoce (fitamiin B12 (hydroxocobalamin)) ayaa looga baahan yahay hematopoiesis -ka caadiga ah (waxay kor u qaadaa korriinka unugyada dhiigga cas).
Wuxuu ka qayb qaataa geeddi -socodka transmethylation, gaadiidka hydrogen, isku -darka methionine, acids nucleic, choline, creatine. Waxay gacan ka geysataa isku -ururinta erythrocytes ee xeryahooda ay ku jiraan kooxaha sulfhydryl.
Farmashiyaha
Maamulka afka ka dib, Tribedoce (fitamiin B12 (hydroxocobalamin)) ayaa laga nuugaa mareenka caloosha. Metabolized ee unugyada, noqoshada nooc ka mid ah coenzyme - adenosylcobalamin, oo ah qaabka firfircoon ee cyanocobalamin. Waxaa laga soo saaray xameetida iyo kaadida.
Maxaa loo qoraa Tribedoce)?
Dhiig -yaraanta oo ay ugu wacan tahay xaalado yaraanta B12; daaweynta adag ee birta iyo dhiig-yaraanta dhiig-baxa kaddib; dhiig -yarida aplastic oo ay keento walxaha sunta ah iyo daawooyinka; cudurka beerka (cagaarshow, cirrhosis); myelosis funicular; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; curyaanka maskaxda ee dhallaanka, Down syndrome, dhaawaca dareemayaasha durugsan; cudurrada maqaarka (cudurka psoriasis, fotodermatosis, dermatitis herpetiformis, neurodermatitis); si looga hortago loona daweeyo astaamaha Tribedoce (fiitamiin B12 (hydroxocobalamin)) yaraanta (oo ay ku jirto adeegsiga biguanide, PASA, fitamiin C oo qaadasho sare leh); shucaaca
Qiyaasta iyo maamulka
Tribedoce) waxaa loo isticmaalaa SC, IV, IM, intralumbar iyo irbadaha afka. Iyada oo la xiriirta dhiig-yaraan la xiriirta yaraanta Tribedoce (fitamiin B12 (hydroxocobalamin)) ayaa lagu soo saaraa 100-200 mcg 2 maalmood gudahood.
In dhiig -yaraan oo leh astaamaha myelosis funicular iyo megalocytic anemia oo leh cudurro habdhiska dareenka: 400-500 mikrogram 7da maalmood ee ugu horreeya maalintii, ka dibna 1 jeer 5-7 maalmood kasta.
Xilliga cafiska ee maqnaanshaha dhacdooyinka qiyaasta dayactirka ee myelosis funicular - 100 mcg 2 jeer bishii, iyadoo ay jiraan astaamaha neerfaha - illaa 200-400 mcg 2-4 jeer bishii.
Xaalad degdeg ah oo dhiig-yaraanta dhiig-baxa kaddib iyo dhiig-yarida birta 30-100 mcg 2-3 jeer toddobaadkii. Marka dhiig -yarida aplastic (gaar ahaan carruurta) - 100 microgram ka hor hagaajinta caafimaad.
Marka dhiig -yaraanta nafaqada ee dhallaanka iyo dhallaanka dhiciska ah - 30 mcg / maalin muddo 15 maalmood ah.
Xanuunada habdhiska dareenka dhexe iyo durugsan iyo cudurrada neerfaha ee leh xanuunka xanuunka waxaa lagu maamulaa qaddarro sii kordhaya - 200-500 mcg, iyada oo la hagaajinayo gobolka - 100 mcg / maalin.
Koorsada daaweynta Tribedoce (fitamiin B12 (hydroxocobalamin)) waa 2 toddobaad. Dhaawacyada naxdinta leh ee nidaamka dareemayaasha durugsan: 200-400 mcg maalin kasta 40-45 maalmood.
Marka cagaarshow iyo cirrhosis: 30-60 mcg / maalin ama 100 mg maalin kasta 25-40 maalmood.
Dystrophy ee carruurta yaryar, Down syndrome iyo curyaanka maskaxda: 15-30 mcg maalin kasta.
Marka myelosis funicular, amyotrophic lateral sclerosis waxaa lagu soo bandhigi karaa kanaalka laf-dhabarka 15-30 mcg, si tartiib tartiib ah u kordhisa qiyaasta 200-250 microgram.
Xanuunka shucaaca, neeropathy macaanka, wuxuu ka soo baxaa 60-100 mcg maalintii 20-30 maalmood.
Marka Tribedoce (Vitamin B12 (Hydroxocobalamin)) yaraanta si looga hortago - IV ama IM 1 mg 1 mar bishii; daaweynta: IV ama IM 1 mg maalintii muddo 1-2 toddobaad ah, qiyaasta dayactirku waa 1-2 mg IV ama IM muddo 1 toddobaad ah, illaa 1 bishiiba. Muddada daaweynta waxaa loo go'aamiyaa si gaar ah.
xayeysiis
Qabiilka laba iyo toban waxyeellooyin, falcelin xun
CNS: marar dhif ah, xaalad xamaasad leh.
Nidaamka wadnaha: dhif iyo naadir - xanuunka wadnaha, tachycardia.
Dareen -celinta xasaasiyadda: marar dhif ah - finan.
Qabiil) ka -hortagga
Thromboembolism, erythremia, erythrocytosis, kordhinta xasaasiyadda cyanocobalamin.
Tribedoce) inta lagu jiro uurka iyo nuujinta
Cyanocobalamin waxaa loo isticmaali karaa uurka iyadoo la raacayo cuntooyinka.
Tilmaamo gaar ah
Marka stenocardia waa in si taxaddar leh loogu adeegsadaa hal qiyaas oo ah Tribedoce) 100 mcg. Inta lagu jiro daaweynta sawirka dhiigga iyo xinjirowga waa in si joogto ah loo hubiyaa. Waa wax aan la aqbali karin in lagu geliyo isla irbadda leh xalalka thiamine iyo pyridoxine cyanocobalamin.
Qabiilka laba iyo toban isdhexgal
Codsiga Tribedoce (Fiitamiin B12 (Hydroxocobalamin)) oo leh ka hortagga hormoonnada ee maamulka afka ayaa yareyn kara uruurinta cyanocobalamin ee plasma.
Codsiga daawooyinka ka hortagga uurka, nuugista cyanocobalamin ee xiidmaha ayaa hoos u dhacday.
Codsiga Tribedoce (Fiitamiin B12 (Hydroxocobalamin)) oo leh neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, daawooyinka potassium waxay hoos u dhigeen nuugista cyanocobalamin mindhicirka.
Cyanocobalamin waxay ka sii dari kartaa falcelinta xasaasiyadda ee ay keento thiamine.
Marka codsiga waalidka ee chloramphenicol uu yarayn karo saamaynta hematopoietic ee cyanocobalamin oo leh dhiig -yaraan.
Iswaafajinta dawada
Ka kooban molecule ion cobalt ee cyanocobalamin wuxuu gacan ka geystaa burburinta ascorbic acid, thiamine bromide, riboflavin ee xalka.
xayeysiis
Maaddooyinka firfircoon ee dawooyinka Tribedoce oo ay ku jiraan magaca sumadda iyo dawooyinka guud ee la xiriira:
Walaxda firfircoon waa qayb ka mid ah daroogada ama daroogada oo bayooloji ahaan firfircoon. Qaybtan dawadu waxay mas'uul ka tahay ficilka ugu weyn ee dawada ee loogu talagalay in lagu daaweeyo ama lagu yareeyo astaamaha ama cudurka. Qaybaha kale ee daroogada ee aan firfircoonayn waxaa loogu yeeraa kaabiyayaal; Doorkeedu waa inuu u dhaqmo sida baabuur ama xayndaab. Si ka duwan maaddooyinka firfircoon, doorka maadada aan firfircoonayn muhiim kuma aha daaweynta ama daaweynta cudurka. Waxaa jiri kara hal ama in ka badan oo ka mid ah maaddooyinka firfircoon ee daroogada.
- Vitamin B1 (thiamine hydrochloride)
- Fiitamiin B12 (hydroxocobalamin)
- Fiitamiin B6 (pyridoxine hydrochloride)
Laba iyo toban shirkadood oo dawooyinka sameeya:
Shirkadaha dawadu waa shirkado soo saarta dawooyinka oo gacan ka geysta horumarinta dawooyinka oo dhan, laga bilaabo cilmi -baadhista hore ilaa tababarka, tijaabooyinka caafimaad, sii -deynta daroogada ilaa suuqa, iyo ka ganacsiga daroogada.
Cilmi -baadhayaashu waa dadka mas'uulka ka ah cilmi -baadhista sayniska iyo dhammaan tijaabooyinkii caafimaad ee hore ee keenay soo -saarka dawada.
Su'aalaha soo noqnoqda
Ma wadi karaa baabuur ama ma shaqayn karaa mashiinno culus ka dib markaan qaato Tribedoce?
Iyada oo ku xidhan falcelinta Tribedoce ka dib qaadashada, haddii aad dareento dawakh, lulo ama falcelin daciif ah oo jidhkaaga ah, ka dibna tixgeli in Tribedoce aysan ammaan u ahayn wadista ama ku shaqaynta mashiinnada culus isticmaalka kadib.
Taas oo macnaheedu yahay ha kaxayn baabuur ama ha ku shaqayn mashiinno culus ka dib markaad kaabsalka qaadato haddii kaabsalku jidhkaaga ku leeyahay falcelin la yaab leh sida dawakhaad, lulmo. Sida uu qoray farmashiistaha, waa khatar in la cabo aalkolo marka la qaadanayo daawada, maadaama ay bukaanka u soo bandhigto hurdo iyo halis caafimaad.
Ka digtoonow saameyntan, gaar ahaan markaad qaadanayso kaabsoolka Primosa. Waxaa lagugula talinayaa inaad la tashato dhakhtarkaaga waqtiga si aad u hesho talo habboon iyo la -talin caafimaad. Qabiilku ma qabatimaa mise caado baa samaysata?
Daawooyinka looma qorshayn iyada oo ujeedadu tahay in lagu abuuro balwad ama xadgudub caafimaadka dadka isticmaala. Daawooyinka balwadda waxaa si gaar ah loogu yeeraa walxaha ay dowladdu maamusho. Tusaale ahaan, Jadwalka H ama X ee Hindiya iyo Jadwalka II-V ee Maraykanka waa walxaha la kontoroolo.
Fiiri buugga tilmaamaha daroogada sida loo isticmaalo oo hubi in aysan ahayn walax la kontoroolo. Gabagabadii, is-daaweyntu waxay u dhimaysaa caafimaadkaaga. La tasho dhakhtarkaaga si aad u hesho warqad sax ah, talo bixin, iyo hagitaan.
Xad -dhaaf
Haddii uu qof xad dhaaf noqdo oo uu leeyahay calaamado daran sida suuxdin ama neefta oo ku qabata, wac 911. Haddii kale, isla markiiba wac xarunta xakamaynta sunta. Dadka deggan Mareykanka waxay wici karaan xaruntooda xakamaynta sunta ee 1-800-222-1222 . Deganeyaasha Kanada waxay wici karaan xarunta xakamaynta sunta ee gobolka. Calaamadaha xad -dhaafka ah waxaa ka mid noqon kara: qalal.
Xusuusin
Ha la wadaagin dawadan dadka kale. Baaritaannada shaybaarka iyo / ama caafimaadka (sida tirada dhiigga oo dhammeystiran, baaritaannada shaqada kelyaha) waa in la sameeyaa inta aad isticmaaleyso dawadan. Ilaali dhammaan ballamaha caafimaadka iyo shaybaarka.
Kaydinta
La tasho tilmaamaha badeecada iyo farmashiistahaaga faahfaahinta kaydinta. Daawooyinka oo dhan ka ilaali carruurta iyo xayawaanka guriga, ha ku daadin daawooyinka musqusha ama ha ku shubin biyo mareen haddii aan lagu amrin. Si habboon u tuur badeecadan marka ay dhacdo ama aan loo baahnayn. La tasho farmashiistahaaga ama shirkadda qashin -qubka ee deegaankaaga.
Afeef: Wasiirradu waxay sameeyeen wax kasta oo suurtogal ah si loo hubiyo in dhammaan macluumaadka ay sax yihiin, dhammaystiran yihiin oo la cusboonaysiiyay. Si kastaba ha ahaatee, maqaalkan waa inaan loo isticmaalin beddelka aqoonta iyo waayo -aragnimada xirfadle daryeel caafimaad oo ruqsad haysta. Waa inaad had iyo jeer la tashataa takhtarkaaga ama xirfadle daryeel caafimaad kale ka hor intaadan qaadan wax daawo ah.
Macluumaadka daroogada ee halkan ku jira waa la beddeli karaa loomana jeedo in lagu daboolo dhammaan adeegsiga suurtagalka ah, tilmaamaha, taxaddarrada, digniinta, isdhexgalka daroogada, falcelinta xasaasiyadda, ama saamaynta xun. Maqnaanshaha digniinta ama macluumaad kale oo loogu talagalay daawo gaar ah ma tilmaamayso in isku -darka daroogada ama daroogadu ay badbaado tahay, wax ku ool tahay, ama ku habboon tahay dhammaan bukaan -socodka ama dhammaan isticmaalka gaarka ah.
Tixraacyada
- DailyMed. ACID ASCORBIC; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; ACID FOLIC; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; TIYAAMIIN; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed waxay bixisaa macluumaad lagu kalsoonaan karo oo ku saabsan dawooyinka suuqyada ee Maraykanka. DailyMed waa bixiyaha rasmiga ah ee macluumaadka sumadda FDA (gelinta xirmada) .. https://dailymed.nlm.nih.gov/dailyme… (waxaa la helay Sebtember 17, 2018).
- DailyMed. DICLOFENAC EPOLAMINE: DailyMed waxay bixisaa macluumaad lagu kalsoonaan karo oo ku saabsan dawooyinka suuqyada ee Maraykanka. DailyMed waa bixiyaha rasmiga ah ee macluumaadka sumadda FDA (gelinta xirmada) .. https://dailymed.nlm.nih.gov/dailyme… (waxaa la helay Sebtember 17, 2018).
- PubChem. diclofenac. https://pubchem.ncbi.nlm.nih.gov/com… (waxaa la helay Sebtember 17, 2018).
- PubChem. thiamine. https://pubchem.ncbi.nlm.nih.gov/com… (waxaa la helay Sebtember 17, 2018).
- PubChem. pyridoxine. https://pubchem.ncbi.nlm.nih.gov/com… (waxaa la helay Sebtember 17, 2018)
Tusmada
- Ficilka dawooyinka
- Farmashiyaha
- Maxaa loo qoraa Tribedoce)?
- Qiyaasta iyo maamulka
- Qabiilka laba iyo toban waxyeellooyin, falcelin xun
- Qabiil) ka -hortagga
- Tribedoce) inta lagu jiro uurka iyo nuujinta
- Tilmaamo gaar ah
- Qabiilka laba iyo toban isdhexgal
- Maaddooyinka firfircoon ee dawooyinka Tribedoce oo ay ku jiraan magaca sumadda iyo dawooyinka guud ee la xiriira:
- Laba iyo toban shirkadood oo dawooyinka sameeya:
- Su'aalaha soo noqnoqda
- Xad -dhaaf
- Xusuusin
- Kaydinta
- Erayada Dhiirrigelinta oo beddeli kara noloshaada
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